• 1st 'class 1 software medical device' for HE
  • 6 cognitive tests
  • Developed in 10 months

In Europe, 200,000 people are affected by Hepatic Encephalopathy (HE), a potentially fatal condition caused by chronic liver disease. Norgine wanted to develop an app to help patients monitor symptoms anytime, anywhere.


Empowering liver disease patients to recognise the early signs of HE can help them seek medical support sooner, reduce their risk of developing irreversible brain damage and potentially death.

Our solution

HE is a common and under-diagnosed complication of liver cirrhosis which causes a decline in brain function which can end up in coma and ultimately death.

Patients may experience HE episodes anytime, but the symptoms are not unique to the disease, making it difficult for patients and their carers to proactively seek help and support between clinic appointments.

earthware designed and built LiverSync®, a free app for patients and carers and an associated web portal for HCPs, to allow patients to complete simple cognitive tests that can monitor trends in their brain function and memory.

Accessed via a smartphone, the app can be used anytime, anywhere. Patients can share information from the app with carers and healthcare professionals, helping them to get a diagnosis and treatment as early as possible.

How was the experience?

This was Norgine's first software as a medical device which meant we were starting a nerve-wracking journey into the unknown. We chose earthware to be our partners because I know I can trust them to be honest and helpful throughout. We have a great relationship with the team that allows us to get things done super efficiently as a true partnership.

Kym Jacks-Bryant

Head of Digital Centre of Excellence, Norgine

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